This book is dedicated to Uffe Ravnskov, MD, Ph.D. for his seminal and propaedeutic achievements in disputing the dogma that fat and cholesterol cause coronary heart disease, and that statins are safe and cardioprotective for everyone. As will be seen, no studies support the notion that restricting fat reduces coronary morbidity or mortality. More importantly, government recommendations mandating low fat diets are likely the cause of the escalating epidemic of obesity and type 2 diabetes.

Several chapters detail the panoply of significant adverse health effects of statins that have been ignored or suppressed in reports of drug company sponsored trials. These include promoting the development of coronary atherosclerosis and congestive failure. In addition, the putative benefits of statins are clearly unrelated to lowering LDL or cholesterol, but rather anti-inflammatory and especially anticoagulant activities. This clotting or "atherothrombotic" hypothesis appears to explain all of the factors known to cause or protect against coronary heart disease. Other chapters by THINCS members discuss the role of infections and sulfur deficiency, and the numerous ways data are doctored to hype the benefits and minimize the dangers of statins.

All of these contributions expose the fallacies of the lipid hypothesis, which was called "the greatest scientific deception of this century, perhaps of any century" by the distinguished nutritionist George Mann, former Co-Director of the Framingham Study.

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• Science & MathsMedicine

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